50 First Dates, 2004

Who: Drew Barrymore, Adam Sandler
What: Henry (Sandler) is a serial dater until meets his perfect woman, Lucy (Barrymore). Unfortunately she suffers from short-term memory loss, meaning every day is a blank slate and she can’t remember Henry chatting her up. Cue Henry wooing her afresh every day.
Defining moment: When Henry and Lucy spend the night together, she wakes up with her memory wiped and what she thinks is a stranger next to her. So she beats the shit out of him with a lacrosse stick.