My Sister's Keeper, 2009

Who: Cameron Diaz, Abigail Breslin, Sofia Vassilieva, Alec Baldwin
What: Anna (Breslin) was genetically engineered before birth so that she would be a bone marrow match for her leukaemia-stricken older sister (Vassilieva). Now 13, she wants medical emancipation from her parents so she isn’t forced to undergo any more of the surgeries required to help keep her sister alive.
Weepy rating: It’s based on a Jodi Picoult novel. Along with Nicholas Sparks, this is shorthand for ‘sobfest’.